1,000 mcg B12 Under the Tongue4.8/5 · 3,000+ Reviews on Trustpilot

CankerShield B12 Sublingual Melts

Always have a canker sore? Stop treating the sore. Feed the lining of your mouth.*


  • Tired of numbing gels that wear off? One melt a night works from the inside, nothing to dab on the sore*
  • 1,000 mcg vitamin B12 + folate, zinc, D3 to support a healthy, resilient mouth lining*
  • 1 melt under your tongue at night, sugar-free, mint-free, no stinging
FREE with every order: the Healthy Mouth Guide, with the one toothpaste ingredient to avoid.
Estimated delivery:

Why should I subscribe?

  • Free shippingon your 1st order
  • Save up to 34%on every delivery
  • Pause or cancelany time
  • Never run outit ships automatically
Add the 20% code by clicking here:
90-Day Risk-Free TrialTry it for 90 days. Not happy? Get a full refund.
How does CankerShield work?

Gels, patches and rinses all go on the canker sore that's already there. But the lining of your mouth rebuilds itself every couple of weeks, and to do it, it needs vitamin B12, folate and zinc. Research shows that people who get canker sores again and again are more often low in these nutrients. CankerShield gives your mouth lining what it rebuilds with, every night, from the inside.*

How do I take it?

Every evening after brushing, place one melt under your tongue and let it dissolve. Don't chew it, and wait a few minutes before eating or drinking.

Why under the tongue?

The melt dissolves right where the B12 is absorbed, through the thin lining under your tongue, instead of having to go through your stomach first. It's also the form used in the vitamin B12 research.

Will it stop my canker sores?

We can't promise that, and nobody honestly can. CankerShield is made to support a healthy, resilient mouth lining.* Many canker sores also have triggers like stress, a bitten cheek or acidic foods. Keep taking it every night for at least 3 months.

How quickly will I notice a difference?

This is not an instant fix: your mouth lining needs time to rebuild. In vitamin B12 research, the difference showed up after several months of nightly use. Give it at least 3 months. That's why every order comes with our 90-day money-back guarantee.

What is the free Healthy Mouth Guide?

A short digital guide sent with every order: the simple daily habits that keep a sensitive mouth calmer, including the foaming ingredient found in many toothpastes that you may want to avoid.

Everything your mouth lining needs. Nothing that stings.

1,000 mcg Vitamin B12

Absorbed Under the Tongue

Folate, Zinc & Vitamin D3

Sugar-Free, Mint-Free

1 Melt Every Night

90-Day Money-Back Guarantee

Sound familiar? It's not just bad luck.

There's always one

"I literally always have a canker sore." One heals, and the next one is already starting.

  • ✓Supports a healthy mouth lining every night*
  • ✓Works from the inside, not on the sore
  • ✓Built for the long run
Eating hurts

It hurts so much you can't even eat. You chew on one side, skip meals and avoid anything acidic or crunchy.

  • ✓Nothing to put on the sore
  • ✓No stinging, no numbing, no taste
  • ✓Supports a resilient lining*
You've tried everything

Salt, alum, peroxide, numbing gels that last 20 minutes, patches that slide off. A drawer full of half-used tubes.

  • ✓One simple step instead of 10 remedies
  • ✓Under the tongue, before bed
  • ✓Under $1.30 a day on subscription
Nobody has an answer

Your doctor says they "just happen" and tells you to stress less. Your blood test came back "normal".

  • ✓Made for people whose canker sores keep coming back
  • ✓B12 in the form used in research
  • ✓90-day money-back guarantee
Why the next one keeps coming

Gels treat the sore. Your problem is the lining underneath.

The lining of your mouth replaces itself every couple of weeks. When it rebuilds thin, a small bite or a stressful week is enough to break it open.

How CankerShield feeds the mouth lining from the inside

To rebuild that fast, your mouth lining burns through vitamin B12, folate and zinc. Studies show that people who get canker sores again and again are more often low in these nutrients. Every gel, patch and rinse works on the surface of the sore. CankerShield works on the lining itself, every night, from the inside.*

1. Outside: soothe the sore

Gels and rinses can help the sore you have today feel better for a while.

GelsPatchesRinses

2. Inside: feed the lining

One melt under your tongue gives your mouth lining what it rebuilds with, so it can stay strong between flare-ups.*

Vitamin B12FolateZincVitamin D3

Sugar-free. Mint-free. Nothing to dab on the sore.

What's inside

Four nutrients. One melt. Nothing that stings.

No lysine, no strong mint, no sugar. Just what research points to for a healthy mouth lining.

CankerShield ingredients: vitamin B12, folate, zinc, vitamin D3
Mouth lining

Vitamin B12 (1,000 mcg)

Helps your body make new cells, including the cells of your mouth lining. Absorbed under the tongue.*

In a placebo-controlled study, people with recurring canker sores took 1,000 mcg of vitamin B12 under the tongue every night. At 6 months, 74% had no canker sore, compared with 32% in the placebo group.

Cell renewal

Folate (methylfolate)

Works with B12 to support healthy cell division and tissue renewal.*

In research, people with recurring canker sores were more often low in folate.

Tissue repair

Zinc

Supports normal tissue repair and immune function.*

Studies found lower zinc levels in people with recurring canker sores.

Natural defenses

Vitamin D3

Supports a normal immune response.*

Studies found lower vitamin D levels in people with recurring canker sores.

Study results refer to research on individual nutrients, not to the CankerShield formula.

Why nothing has worked so far

Everything else goes on the sore. CankerShield works on the lining.

If you've tried numbing gels, salt and patches and there's still always a new one, here's why.

Numbing gels Patches Salt & rinses CankerShield
Works on the mouth lining from inside*✕✕✕✓
No stinging or burningOften not✓✕✓
Nothing to put on the sore✕✕✕✓
Lasts all day and night✕Partly✕✓
One step, once a day✕✕✕✓
Money-back guarantee✕✕✕90 days
What to expect

A stronger mouth lining, month after month

CankerShield is not a quick fix. It builds up night after night.

Tonight

A new night habit

Brush your teeth, then let one melt dissolve under your tongue. That's it. Keep soothing any sore you have today as usual.

Months 1–2

Your lining rebuilds

Your mouth lining renews itself every couple of weeks, with the nutrients it needs this time.*

Month 3+

Stay consistent

In vitamin B12 research, the difference showed up after several months of nightly use. Keep going every night.*

Individual results vary.

Is CankerShield for you?

Made for adults whose canker sores keep coming back

You always have one

One heals on the left, another opens on the right.

They show up when life gets hard

Exams, deadlines, night shifts, or every month before your period.

You suspect a deficiency

You've read about B12, but your blood test came back "normal" or the pills you swallowed did nothing.

You're done with gels and salt

You want one simple step that works from the inside, with nothing that stings.

CankerShield doesn't replace medical care. A mouth sore that lasts more than 3 weeks should be checked by a dentist or doctor.

Try it for 90 days, risk-free

Take CankerShield every evening for 90 days. If you're not completely happy, email us and we'll refund every penny. No questions asked.

Get CankerShield

Frequently Asked Questions

How long does one jar last?

One jar of 30 melts lasts 30 days at one melt every evening.

What does it taste like?

It has a mild, neutral taste, with no strong mint or cinnamon that could irritate a sensitive mouth, and no sugar.

Can I take it if I have a canker sore right now?

Yes. It goes under your tongue, not on the sore. You can keep using what soothes your sore today.

Why no L-lysine?

Lysine is mostly studied for cold sores on the lips, which are different from canker sores inside the mouth. We kept only the nutrients research points to for the mouth lining.

Who should not take CankerShield?

If you are pregnant, nursing, taking medication or have a medical condition, ask your healthcare provider before use. Do not exceed one melt a day. Keep out of reach of children.

Can I pause or cancel my subscription?

Anytime. Skip a delivery, change your frequency or cancel in a few clicks from your account, or just send us an email. No fees, no commitment.

What is your return policy?

Try CankerShield for 90 days. If you're not completely satisfied, contact us and we'll give you a full refund.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Study results mentioned on this page refer to research on vitamin B12 and other individual nutrients, not to the CankerShield formula. Do not exceed the recommended dose. Keep out of reach of children. If you are pregnant, nursing, taking medication or have a medical condition, ask your healthcare provider before use. A mouth sore that lasts more than 3 weeks should be checked by a dentist or doctor.

CankerShieldSave up to 34% · 90-day guarantee
Shop now